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Healthy Longevity Top 10 Supplements

I’ll start by analyzing 3 top references and then compile a combined top 10 list of healthy life extension supplements.

National Institute on Aging (NIA) Interventions Testing Program (ITP)

The NIA ITP is a peer-reviewed program designed to identify agents that extend lifespan and healthspan in mice. Some of the interventions tested include:

  • Acarbose: Reduces glucose levels, extends lifespan.
  • Aspirin: Anti-inflammatory, extends lifespan.
  • Astaxanthin: Antioxidant, extends lifespan.
  • Canagliflozin: Diabetes medication, extends lifespan.
  • Captopril: Blood pressure medication, extends lifespan.
  • Glycine: Amino acid, extends lifespan.
  • Meclizine: Antihistamine, extends lifespan.
  • Nordihydroguaiaretic Acid (NDGA): Antioxidant, extends lifespan.
  • Protandim®: Herbal supplement, extends lifespan.
  • Rapamycin: Immunosuppressant, extends lifespan.
  • 16-hydroxyestriol: Estrogen derivative, extends lifespan.
  • 17α-estradiol: Estrogen derivative, extends lifespan.

Bryan Johnson’s Supplement Stack

Bryan Johnson, a longevity enthusiast, takes a robust supplement regimen. Some of the key supplements he uses include:

  • Calcium Alpha-ketoglutarate (Ca-AKG): Improves frailty index, extends lifespan.
  • Nicotinamide Riboside (NR) / Nicotinamide Mononucleotide (NMN): Raises NAD levels, supports longevity.
  • Taurine: Extends lifespan.
  • Nordihydroguaiaretic Acid (NDGA): Extends lifespan.
  • Aspirin: Anti-inflammatory, extends lifespan.
  • Ashwagandha: Reduces anxiety, improves cortisol management.
  • BroccoMax / Sulforaphane: Chemoprotection.
  • Cocoa Flavanols: Heart and brain health.
  • Longevity Mix: Supports energy, metabolism, recovery, vitality.
  • Elite Protein Powder: Plant-based protein for muscle building.

David Sinclair’s Supplement Stack

David Sinclair, a leading researcher in aging, follows a specific supplement regimen based on longevity research. Some of the key supplements he uses include:

  • Resveratrol: Anti-inflammatory, extends lifespan.
  • Nicotinamide Mononucleotide (NMN): Raises NAD levels, supports longevity.
  • Spermidine: Extends lifespan.
  • TMG (Trimethylglycine): Supports methylation.
  • Metformin: Diabetes medication, extends lifespan.
  • Aspirin: Anti-inflammatory, extends lifespan.
  • Vitamin D3: Bone health, immune support.
  • Vitamin K2: Bone health, cardiovascular support.
  • Omega-3 Fish Oil: Heart health, cognitive function.
  • Alpha Lipoic Acid (ALA): Antioxidant, supports energy metabolism.
  • Coenzyme Q10: Antioxidant, supports energy production.
  • Quercetin: Antioxidant, anti-inflammatory.
  • Fisetin: Antioxidant, anti-inflammatory.
  • Taurine: Extends lifespan.

Combined Top 10 Healthy Life Extension Supplements

Based on the information from the NIA ITP, Bryan Johnson, and David Sinclair, here’s a combined top 10 list of healthy life extension supplements:

  1. Resveratrol: Anti-inflammatory, extends lifespan.
  2. Nicotinamide Mononucleotide (NMN): Raises NAD levels, supports longevity.
  3. Aspirin: Anti-inflammatory, extends lifespan.
  4. Calcium Alpha-ketoglutarate (Ca-AKG): Improves frailty index, extends lifespan.
  5. Taurine: Extends lifespan.
  6. Astaxanthin: Antioxidant, extends lifespan.
  7. Omega-3 Fish Oil: Heart health, cognitive function.
  8. Vitamin D3: Bone health, immune support.
  9. Alpha Lipoic Acid (ALA): Antioxidant, supports energy metabolism.
  10. Coenzyme Q10: Antioxidant, supports energy production.

You can search for these supplements online or use the company we use.

Remember…it is best to consult your doctor before starting any supplements.

Author gnd and CoPilot